职员
  • 学术带头人
  • 功能影像
  • 分子影像
  • 孙少凯 医学影像学院

    机构:天津医科大学

    部门:医学影像科

    邮箱:shaokaisun@tmu.edu.cn

    地址:天津市河西区广东路1号


    个人简介:

    天津医科大学医学影像学院副教授,硕士生导师。2013年6月于获得南开大学分析化学专业博士学位。2013年7月至今就职于天津医科大学医学影像学院。研究领域为肿瘤/神经分子影像。以第一作者/通讯作者在Advanced Materials (IF: 25.809)、Accounts of Chemical Research (IF: 21.661)、Advanced Functional Materials (IF: 15.621)和Biomaterials (IF: 10.273)等杂志发表SCI论文18篇,累计影响因子为154.139,其中影响因子>10分论文4篇,单篇最高影响因子为25.809。获批国家发明专利1项。担任Advanced Materials、Advanced Functional Materials和Advanced Science等十余个国际期刊审稿人。入选第二批天津市青年人才托举工程(2018)、天津市“131人才工程”第二层次(2016)、天津医科大学卓越教师发展支持计划(2018)和天津市创新人才推进计划青年优秀科技人才(2018)。


    教育经历:

    2008/09–2013/06,南开大学,分析化学专业(博士),导师 严秀平。


    科研与学术工作经历:

    1.2013/07–2016/12,天津医科大学,医学影像学院,讲师。

    2.2017/01–至今,天津医科大学,医学影像学院,副教授。


    主持或参加科研项目及人才计划项目情况:

    1. 第二批天津市青年人才托举工程(2018),2019/01至2021/12,45万元,在研,主持。

    2. 国家自然基金面上项目,21874101,长余辉纳米疫苗的构建及其在免疫细胞示踪和肿瘤治疗中的应用,2019/01至2022/12,66万元,在研,主持。

    3. 天津市自然基金面上项目,18JCYBJC20800,基于仿生技术构建超高抗原负载量的多功能纳米疫苗,2018/04至2021/03,10万元,在研,主持。

    4. 国家自然基金青年项目,21405112,以白蛋白为模板构建肿瘤靶向的近红外光学/磁共振成像和基因治疗一体化探针,2015/01至2017/12,25万元,已结题,主持。

    5. 国家自然基金重点项目,21435001,新型多功能纳米探针的构建及其在生物成像中的应用,2015/01至2019/12,60万元,在研,参与。


    代表性研究成果:

    一、期刊论文

    1.第一作者论文

    (1)Shao-Kai Sun#, He-Fang Wang#, and Xiu-Ping Yan*. Engineering Persistent Luminescence Nanoparticles for Biological Applications: From Biosensing/Bioimaging to Theranostics. Accounts of Chemical Research 2018, 51 (5), 1131-1143. IF: 21.661

    (2)Shao-Kai Sun, Lu-Xi Dong, Yang Cao, Hao-Ran Sun, Xiu-Ping Yan*. Fabrication of multifunctional Gd2O3/Au hybrid nanoprobe via a one-step approach for near-infrared fluorescence and magnetic resonance multimodal imaging in Vivo, Analytical Chemistry, 2013, 85(17), 8436-8441. IF: 6.35

    (3)Shao-Kai Sun, Bei-Bei Wang, Xiu-Ping Yan*. A label-free near-infrared fluorescent assay for the determination of deoxyribonuclease I activity based on malachite green/G-quadruplexes, Analyst, 2013, 138(9), 2592-2597. IF: 4.019

    (4)Shao-Kai Sun, Kai-Xiong Tu, Xiu-Ping Yan*. An indicator-displacement assay for naked-eye detection and quantification of histidine in human urine, Analyst, 2012, 137(9), 2124-2128. IF: 4.019

    (5)Shao-Kai Sun, He-Fang Wang, Xiu-Ping Yan*. Sensitive and selective resonance light scattering bioassay for homocysteine in biological fluids based on target-involved assembly of polyethyleneimine-capped Ag-nanoclusters, Chemical Communications, 2011, 47(13), 3817-3819. IF=6.29

    (6)Jinbin Pan#, Shao-Kai Sun#, Yaqiong Wang, Yan-Yan Fu, Xuejun Zhang, Yi Zhang, Chunshui Yu*. Facile preparation of hyaluronic acid and transferrin co-modified Fe3O4 nanoparticles with inherent biocompatibility for dual-targeting magnetic resonance imaging of tumors in vivo. Dalton Transactions, 2015, 44 (46), 19836-19843. IF: 6.164

    2.通讯作者论文

    (1)Haoyu Wang, Limei Jiang, Huanhuan Wu, Weiya Zheng, Di Kan, Ran Cheng, Juanjuan Yan, Chunshui Yu* and Shao-Kai Sun*, Biocompatible Iodine–Starch–Alginate Hydrogel for Tumor Photothermal Therapy. ACS Biomaterials Science & Engineering 2019, Accepted. IF: 4.511

    (2)Weihua Liao, Peng Lei, Jinbin Pan, Cai Zhang, Xianting Sun, Xuejun Zhang, Chunshui Yu*, Shao-Kai Sun*, Bi-DTPA as a high-performance CT contrast agent for in vivo imaging. Biomaterials 2019, 203, 1-11. IF: 10.273

    (3)Haiyan Pan, Cai Zhang, Tingting Wang, Jiaxi Chen, and Shao-Kai Sun*, In Situ Fabrication of Intelligent Photothermal Indocyanine Green–Alginate Hydrogel for Localized Tumor Ablation. ACS Applied Materials & Interfaces 2019, 11(3), 2782-2789. IF: 8.456

    (4)Hui Zhang, Yue Shang, Yu-Hao Li, Shao-Kai Sun*, and Xue-Bo Yin*, Smart Metal-Organic Framework-Based Nanoplatforms for Imaging-Guided Precise Chemotherapy. ACS Applied Materials & Interfaces 2019, 11(2), 1886-1895. IF: 8.456

    (5)Yaqiong Wang, Jing Zhang, Chuyu Zhang, Bingjie Li, Jiaojiao Wang, Xuejun Zhang, Dong Li*, and Shao-Kai Sun*, Functional Protein-Assisted Fabrication of Fe-Gallic Acid Coordination Polymer Nanonetworks for Localized Photothermal Therapy. ACS Sustainable Chemistry & Engineering 2019, 7(1), 994-1005. IF: 6.97

    (6)Cai Zhang, Haiyan Pan, Xu Wang*, and Shao-Kai Sun*, Microwave-assisted ultrafast fabrication of high-performance polypyrrole nanoparticles for photothermal therapy of tumors in vivo. Biomaterials Science 2018, 6 (10), 2750-2756. IF: 5.251

    (7)Jinbin Pan#, Yaqiong Wang#, Cai Zhang#, Xiaoyi Wang, Haoyu Wang, Jiaojiao Wang, Yizhong Yuan, Xu Wang, Xuejun Zhang, Chunshui Yu, Shao-Kai Sun*, and Xiu-Ping Yan. Antigen-Directed Fabrication of a Multifunctional Nanovaccine with Ultrahigh Antigen Loading Efficiency for Tumor Photothermal-Immunotherapy. Advanced Materials 2018, 30 (8), 1704408. IF: 25.809

    (8)Jinbin Pan#, Yaqiong Wang#, Haiyan Pan, Cai Zhang, Xiaogang Zhang, Yan-Yan Fu, Xuejun Zhang, Chunshui Yu, Shao-Kai Sun*, Xiu-Ping Yan, Mimicking Drug-Substrate Interaction: A Smart Bioinspired Technology for the Fabrication of Theranostic Nanoprobes. Advanced Functional Materials 2017, 27(3), 1603440. IF: 15.621

    (9)Cai Zhang#, Li Zhou#, Jing Zhang, Yan-Yan Fu, Xuejun Zhang, Chunshui Yu, Shao-Kai Sun* and Xiu-Ping Yan. Green and facile synthesis of a theranostic nanoprobe with intrinsic biosafety and targeting ability. Nanoscale 2016, 8 (36), 16204-16211. IF: 6.97

    (10)Boxiong Wei#, Xuejun Zhang#, Cai Zhang, Ying Jiang, Yan-Yan Fu, Chunshui Yu, Shao-Kai Sun* and Xiu-Ping Yan. Facile Synthesis of Uniform-Sized Bismuth Nanoparticles for CT Visualization of Gastrointestinal Tract in Vivo. ACS Applied Materials & Interfaces 2016, 8(20), 12720-12726. IF: 8.456

    (11)Cai Zhang, Yan-Yan Fu, Xuejun Zhang, Chunshui Yu, Yan Zhao and Shao-Kai Sun*. BSA-directed synthesis of CuS nanoparticles as a biocompatible photothermal agent for tumor ablation in vivo, Dalton Transactions, 2015, 44(29), 13112-13118. IF: 4.052

    (12)Haoyu Wang, Yan-Yan Fu, Xuejun Zhang, Chunshui Yu* and Shao-Kai Sun*. Hyaluronic acid-mediated one-pot facile synthesis of a sensitive and biocompatible Gd2O3 nanoprobe for MR imaging in vivo. RSC Advances, 2015, 5 (113), 93041-93047. IF: 3.049